I know damn all about computers.

我对计算机一窍不通。

《牛津词典》

"I know nothing about computers and have never touched a keyboard," he said.

他说：“我对电脑一窍不通，也从来没有碰过键盘。”

youdao

I didn't know much about computers. I still worked on a manual Olivetti typewriter.

我不太懂电脑，仍在用olivetti打字机上工作。

youdao

If history is any indication 72% of the people ; in the theater have no prior programming experience; despite what you may think and despite the fact that some of you may very well be thinking, odds are I know the least about computers than anyone in here, I'm actually a little scared of my computer.

以往的经验表明,大讲堂里72％的人没有任何编程经验;,不管你们怎么想,有些人可能现在就在考虑了，奇怪的是比起在座的各位，我最不了解计算机，我甚至有点怕我的电脑。

哈佛公开课 - 计算机科学课程节选