Peroxynitrites contribute to the hyperphosphorylation of tau proteins by oxidating g-protein coupled receptors and trysoine kinase receptors preventing protein kinase C and AKT from inactivating the enzyme GSK3 which is necessary to prevent the hyperphosphorylation of tau proteins.

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They also scavenge (detoxify) peoxynitrites and reverse part of their damage including partially restoring function to receptors involved in short-term memory, mood, sleep, smell, social recognition, alertness, and brain growth, increasing the transport of glucose reducing delusions and wandering, improving neurotransmissions by decreasing the hyperphosphorylation and tau proteins, and inhibiting the influx of calcium which kills neurons.

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