abstract:Huwentoxins (HWTX) are a group of neurotoxic peptides found in the venom of the Chinese bird spider Haplopelma huwena. While structural similarity can be found among several of these toxins, HWTX as a group possess high functional diversity.
A novel neurotoxic peptide, named huwentoxinIII, and a naturalmutanthave been isolated from the venomof thespider Selenocosmia huwena Wang (Ornithoctonus huwena Wang).