Objective To investigate the expression of membrane type-1 matrix metalloproteinase(MT1-MMP) in human glioma and its relationship to clinicopathological factors and prognosis of glioma patients.
目的探讨膜型基质金属蛋白酶-1在人脑胶质瘤中的表达及其与肿瘤生物学行为和预后的关系。
ConclusionThe expression of MMP-2, TIMP-1 and TIMP-2 are closely correlated with the development of the invasive activity of human astrocytoma.
结论MMP - 2、TIMP - 1和TIMP - 2在星形细胞肿瘤组织中的表达与星形细胞肿瘤的侵袭性生物学行为的演进密切相关。
Conclusion: MMP-2 and MMP-9 be involved in the invasion of the normal human cytotrophoblast cells, while TIMP-1 and TIMP-2 make this invasion controllable.
结论：MMP一2、MMP一9参与了正常早孕滋养细胞的侵袭的过程，而TIMP-1、TIMP一2使滋养层细胞以一种可控制的形式侵袭。
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