METHODS: Using CHO cells which high express human CD59 as target cells, the phage 12 peptide library was screened for 5 rounds by competitive binding test.
方法:以高表达人CD59的中国仓鼠卵巢细胞(CHO)为靶细胞,采用竞争结合试验,对噬菌体随机12肽库进行5轮亲和筛选。
AIM: To screen and identify the short-peptide which specifically bind to human CD59 so as to design short-peptide clamp with counteracting tumor escape activity.
目的:筛选并鉴定与人CD59分子特异结合的短肽,为设计具有拮抗CD59肿瘤逃逸活性的短肽封条奠定基础。
ObjectiveTo establish a cell model expressing human mutant CD59 molecular, and study its biological activities.
目的建立表达人突变CD 59的细胞模型,初步研究其活性。
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