And he also has a huge issue, right?

他还有个大问题是吧？

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"This is a huge issue for society," Kelley said.

凯利说：“这对社会来说是个不小的问题。”

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On one hand, most of the time that's not a huge issue.

其中一方面原因是，在大部分情况下那不是个大问题。

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"For many of the women who walk through our doors, confidence is a huge issue, and I know,many of the women who I've worked with have said to me, 'you know Suzanne, no one has ever said to me, I believe in you,' Elliott says 70 percent of the women helped by the group are single mothers.

VOA: standard.2009.12.25

Cell proliferation is a huge issue in cell culture.

细胞增殖是细胞培养中的重大课题

耶鲁公开课 - 生物医学工程探索课程节选

Now, the reason this condition always holds in ordinary mechanics is because you're never, in that case, concerned with a huge statistical population of particles where the disorder among them is an issue.

这个条件在力学中总是成立,这是因为在力学中,我们从来没有关注过大量粒子的统计行为，而对这些系统来说,无序是很重要的。

麻省理工公开课 - 热力学与动力学课程节选

And, says Litan, the lobbying has been effective because housing is a huge issue.

NPR: Housing Bill Calls For New Fannie-Freddie Regulator

The price of energy was not a huge issue in 2001, but it sure is now.

NPR: Analysis: Congress And The Cost Of Energy

"This is a huge issue, " says Geoffrey Porges, a biotechnology analyst at Sanford C.

FORBES: Chiron's Public Health Disaster