Do you think that the blockage of HMGB-1 could be a strategy to reduce myocardial dysfunction in patients with diabetes?

您认为阻断HMGB-1能够将少糖尿病病人的心血管事件的发生？

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Now we do know that it might be helpful and might be an option to block HMGB-1 binding to RAGE because this binding induces an inflammatory response.

现在我们所知道的是，阻断HMGB - 1结合到RAGE上可能会有益，因为这种结合可以诱导炎症反应。

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Objective to study the changes of serum level of high mobility group box-1 (HMGB - 1) in patients with multiple trauma in order to forecast organ dysfunction (OD) and deaths.

目的研究多发伤患者伤后血清高迁移率蛋白- 1 (HMGB - 1)的水平变化，以预测是否发生脏器功能不全(OD)及死亡率。

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