Despite high mutation detection rate, many HBOC cases remain without identified cause.

尽管有很高的突变检出率，但是许多HBOC仍然没有可识别的原因。

youdao

Ion implantation as a new mutagen caused high mutation rate and wide mutational spectrum with low damage, and it was also mutated in the direction.

离子注入是一种新型的作物诱变技术。离子注入不仅损伤轻，而且突变率高，突变谱广并可定向引变。

youdao

In the trial, which included 55 patients, tumors dramatically shrank in 9 of 16 very advanced patients with the gene mutation who got high doses--a better response rate than doctors have remembered seeing in a trial for advanced melanoma.

FORBES: American Society of Clinical Oncology

By contrast, Japanese patients with another gene mutation were found to have high HDL but no evidence of benefit.

FORBES: Magazine Article