BACKGROUND: -transcatheter aortic valve implantation is an alternative to open heart surgery in patients with aortic stenosis.

背景：除了心内直视手术，经导管主动脉瓣植入术是主动脉狭窄患者的替代治疗方案。

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A total of 358 patients with severe aortic stenosis, a heart disease characterized by obstruction of the aortic valve due to calcification, participated in the trial.

总计358名伴严重主动脉瓣狭窄(特征为因钙化主动脉瓣梗阻的一种心脏病)患者参加了这项实验。

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Reumatic heart disease ; Mitral stenosis; Pulmonary hypertension; Valve replacement.

风湿性心脏病；二尖瓣狭窄；肺高压；瓣膜置换。

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In SEAS, Vytorin failed to do better than placebo at treating a heart valve disease called aortic stenosis, but it did reduce the risk of heart attacks, strokes and operations to unclog arteries.

FORBES: Efficacy Questions Still Dog Vytorin

The blockbuster cholesterol drug Vytorin failed to improve a rare heart valve condition called aortic stenosis and seemed to increase rates of cancer, a new study says, dealing another blow to the top-selling drug and its makers, Merck and Schering-Plough .

FORBES: Another Blow For Merck And Schering