The degree of BME developed progressively with ONFH during early and middle stage before femoral head collapse.

早、中期股骨头未塌陷前，骨髓水肿随着病情的加重而加重；

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In particular, the optimal treatment of extensive osteonecrosis associated with femoral head collapse remains controversial.

尤其股骨头塌陷的广泛骨坏死的最佳治疗仍然是存在争议的。

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Conclusions Data extracted from previously published studies suggest that asymptomatic osteonecrosis has a high prevalence of progression to symptomatic disease and femoral head collapse.

结论：既往文献数据表明无症状性股骨头缺血坏死进展为症状性疾病和股骨头坍塌发生率很高。

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Eventually, however, gravity ensues and the constraints outlined herein raise their head, resulting in a collapse to point C.

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