He cannot possibly mend his own case.
他不能改善自己的境遇。
He cannot possibly take on any further engagements; he's plenty on his plate as it is.
他实在不能承担更多的工作了;他目前要做的事已经够多的。
He thinks his heart is going to stop because he cannot possibly image how this has happened.
他觉得心脏都要停止跳动了,他甚至不能相信这是怎么发生的。
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