Isner's propensity for protracted battles early in majors often saps his energy by the middle rounds, while the Bryans, for all their success on clay in Masters events, haven't reached the French Open final since 2006.
Yeah, things are starting to get a little wild -- we haven't even mentioned the open questions of whether the Zune HD is running Tegra because it's based on Windows Mobile 7 Chassis 1, or whether Pink will launch on Verizon, or whether Zune will appear on other phones, or... you get the idea.