All, have lost direction.

一切，已经失去了方向。

youdao

Have you lost or gained weight recently within 5% in either direction, and have you noticed a significant increase or decrease in appetite?

你是否减少或增加了5%的体重，你是否注意到你有在食欲方面明显的增加或减少？

youdao

Hidden away, they have lost their direction and are in desperate need of hope.

慢慢地，他们失去了方向，现在正急切地需要希望。

youdao

But by the end of my journey, I get the feeling that Russians have lost direction, and that some have lost faith in the man up front who's been driving their locomotive.

BBC: Rosenberg's Russia: On the election trail

The show helped steer her family in a healthier direction, she said, and they all have lost significant amounts of weight.

CNN: 'Big' concerns surround new reality show

As a result, the developers have limited control over a game's direction, and it is never really won or lost.

ECONOMIST: Computer games