Guarente doesn't believe that science could stop aging altogether.

Guarente不相信科学可以解决衰老问题。

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Lenny Guarente: There're just too many things that go wrong in aging, that it would be almost impossible to fix them all at the same time so that you achieve immortality.

在衰老过程中有太多的东西出现问题，几乎没有可能同时再将其修复过来，也就不可能长生不老。

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Lenny Guarente: In mammals, which includes us, what we think is the case, is that calorie restriction - a low calorie diet - triggers anti-aging genes better called sirtuins.

哺乳动物包括我们，在这个问题上，我们认为是卡路里的限制作用-一份低能量食物-触发抗衰老基因，可以称之为“sirtuins”（是一种抗衰老酶）。

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When Guarente's team deleted the sir2 gene from the yeast and then restricted calories, the diet no longer lengthened life span.

FORBES: Researchers are unlocking the mysteries of aging.

Guarente's yeast lived longer when they were given less food, and the underlying mechanism seemed to be that starvation tripped SIR2.

FORBES: Starvation--And Long Life--In A Pill?

This emerged in the lab of MIT biologist Leonard Guarente, whose team spent years counting thousands of yeast cells under a microscope.

FORBES: Researchers are unlocking the mysteries of aging.