The invention discloses a method for a preparing guanidine compound, belonging to the field of organic synthesis.
本发明公开了一种胍类化合物的制备方法，属于有机合成领域。
The chiral guanidine—compound(6)was synthesized from the methyl(R)-phenylglycinate hydrochloride as material and the reaction conditions were investigated.
本文以（R）- 苯基甘氨酸甲酯盐为原料合成了手性胍— 化合物（6），并对合成反应条件进行了探索和优化。
The active hydrogen in the compound (6) might take negative effect in some reactions and was substituted by a methyl to get compound (7) which was a new chiral guanidine.
化合物(6)上与氮相连的活泼氢原子，可能对某些反应有不利影响，故用碘甲烷对其进行甲基取代，得到了新的手性胍—化合物(7)，并做了表征。
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