Mutations in so-called tumor suppressor genes can result in loss of growth control, which in turn may result in cancer.

称之为肿瘤抑制基因的突变可以引起生长失去控制，从而可能导致癌症。

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In 2005, researchers at Sloan-Kettering reported that the gene could stop massive tumor growth in prostate cancer even when another tumor suppressor, known as P53, was turned off.

早在2005年，斯隆·凯特琳中心的研究人员就曾报道了在另一种叫做P 53的肿瘤抑制基因关闭时，该基因甚至仍然可以阻止前列腺癌大肿瘤生长。

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Such chromosomal abnormalities inactivate tumor - suppressor genes that are critical for controlling cell growth.

这种染色体异常使控制细胞生长的关键肿瘤抑制基因失活。

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