选用治疗脑中风等疾病疗效确切的中药活性成分银杏内酯B(Ginkgolides B)作为脑靶向制剂的模型药物。银杏内酯是一类由银杏中分离出的天然产物,包括银杏内酯A、B、C、J、K等。
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正相高效液相色谱法制备银杏内酯A和银杏内酯B 关键词:高效液相制备色谱 银杏内酯A 银杏内酯B [gap=1113]Key words:preparative high-performance liquid chromatography; ginkgolide A; ginkgolide B
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产品中文名称:银杏内酯J英文名:GinkgolideJ中文别名:白果苦内酯J英文别名:GINKGOLIDEJ;7beta-hydroxyginkgolidea;BN52024;GinkgolideA,7-hydro
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Ginkgolide B 银杏内酯B ; 银杏苦内酯B ; 银杏内酯 ; 突起生长
Ginkgolide A 银杏内酯A ; 银杏苦内酯A ; 银杏 ; 缬氨酸
Ginkgolide C 银杏内酯C ; 银杏内酯 ; 亮氨酸
Ginkgolide J 银杏内酯J
Ginkgolide BCAS 银杏内酯B
Ginkgolide CCAS 银杏内酯C
Ginkgolide K 银杏内酯K
Ginkgolide ACAS 银杏内酯A
A Ginkgolide A 银杏内酯
Conclusion This method is suitable for the quality control of Ginkgolide Injection.
结论本法可作为银杏内酯注射液的质量控制方法。
参考来源 - 银杏内酯注射液的HPLC指纹图谱研究Ginkgolide B especially is the most effective agonist of plaque activation factor (PAF) and now become a hot research issue in the medicine field of the world. Now, Flavonoids and ginkgolides were mainly extracted from the leaves of Ginkgo biloba.
尤其银杏内酯B是目前发现的最有效的特异的血小板活化因子(PAF)拮抗剂,已成为世界多国医药专家的研究热点。
参考来源 - 银杏组织、细胞悬浮培养及银杏黄酮和萜内酯的提取、纯化和检测方法研究·2,447,543篇论文数据,部分数据来源于NoteExpress
The purity of the ginkgolide A prepared in this process was above 99%, with the yield of 60%.
该工艺制得的银杏内酯A晶体纯度高于99%,总收率约为60%。
The invention relates to a method for preparing ginkgolide compound, belonging to the medicine field.
本发明属于医药领域,具体涉及一种银杏内酯类化合物制备方法。
Objective: to investigate the effects of Ginkgolide on the apoptosis of cultured neurons in the rat embryonic basal forebrain.
目的:探讨银杏内酯对体外培养的鼠胚基底前脑神经元凋亡的影响。
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