The use of genomic information, accelerated by the sequencing of the human genome and the advent of new tools and technologies, has opened new possibilities in drug discovery and development.
对人类染色体的测序、新工具和新技术的诞生加速了基因组学信息的使用,在药品研发方面开创了新途径。
Polymorphisms exist in human genomic DNA. And some polymorphisms such as metabolic enzymes, drug receptors, and some other genes correlated with diseases may affect the drug responsiveness.
人群中DNA存在多态性,与药物反应相关的基因多态性可能产生药物效应的个体差异,例如药物代谢酶、药物作用受体以及其它一些与疾病相关基因等。
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