The diagnosis was generally not difficult except for 3 cases of misdiagnosis. pharmacotherapy had little effect.

诊断一般不困难，但也有3例误诊，药物治疗基本无效。

youdao

While these symptoms can become overwhelming and debilitating, the good news is, generally speaking, anxiety is not difficult to treat.

这些症状可能变得压倒一切、让人憔悴，另一方面，我们也不必担心，因为总的来说，焦虑是不难治疗的。

youdao

For these types of documents, requiring users to deal with verbose and difficult formats like XML or LaTeX is not generally reasonable, even if those users are programmers.

对于此类文档，通常没有理由要求用户处理象xml或LaTeX这样冗长而又复杂的格式，即使用户是程序员也是如此。

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New techniques used in the study, such as using ultrasound to measure artery plaque, are generally difficult, and not as well understood as cholesterol lowering, they say.

FORBES: Magazine Article

Picking tops or bottoms is generally quite difficult as one often does not have clear technical divergences that can give them enough conviction and discipline to take a position.

FORBES: Finding High-Probability Entry Levels

Democrats generally do not like and do not support cuts in entitlement programs, and yet this President put forward difficult reforms in entitlement programs because he believes that you have to have a balanced approach, you have to include entitlement reform in any effort to reduce our deficit and bring down our -- reduce our debt.

WHITEHOUSE: Press Briefing