Objective:To explore the application of the generalized estimating equation (GEE)in the repeated measures data.

目的：探讨广义估计方程在临床试验重复测量资料分析中的应用。

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Marginal regression model and its associated generalized estimating equation (GEE) are becoming increasingly being used in longitudinal studies.

边际回归模型和与此有关的广义估计方程(GEE)在纵向数据分析中得到了广泛的应用。

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