There is already a targeted treatment for this disease. Gleevec, probably the most remarkable anti-cancer drug of the past decade, disables the protein encoded by another fused gene, BCR-ABL.

现在对这种病已有针对性疗法，Gleevec大体是过去十年中效果最显著的药物，它能使另一融合基因BCR-ABL的编码蛋白失去活性。

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But the kinds of cells they independently studied could not be used to create gene-targeted animals.

但是他们各自所研究的细胞类型不能用来培育基因靶向动物。

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What's so exciting is that virtually any gene can be targeted now.

最让人兴奋的是任何的基因都能成为靶子。

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Strohman was saying this in the face of tremendous hype over gene transplantation and the development of single-gene targeted drugs like Herceptin, Erbitux, Gleevec, Iressa, that have largely been disappointing and very costly.

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Of the new gene-targeted therapies, the one furthest along may be Xinlay from Abbott Laboratories.

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"This is the first gene-targeted medicine in cardiovascular disease, " says Cleveland Clinic's Topol, who is helping design the trial.

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