We have designed a strategy to select new drug targets that inhibit a cellular gene required for HBV replication or restore a response stalled by HBV in the ATR DNA damage pathway.

筛选新的药物靶点可以通过抑制HBV复制必需的一个基因或者保持HBV所引起的AT R损伤途径中的一种失调反应。

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It plays an important role in gene transcription, nuclear hormone receptor signal transduction, apoptosis, and viral replication.

在基因转录，激素受体信号传递，细胞凋亡，病毒复制等方面都有重要作用。

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Objective To investigate the association of polymorphisms of CDT1 and GMNN gene, two important genes participating in DNA replication, with the risk of sporadic breast cancer.

目的探讨参与DNA复制的两个重要基因CDT1和GMNN基因多态性与我国人群散发乳腺癌的关联。

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These cancers are thought to result from energetic particles striking DNA, breaking strands, and interfering with gene replication.

FORBES: 1st Person | Facing an Unsettled Future After Radiation Exposure