Results MFC cells transduced with CD gene exhibited high sensitivity to 5 FC, especially showed the pronounced "bystander effects".

结果转导CD基因可使MFC对5-FC高度敏感，并且显示出强大的“旁观者”效应。

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This gene can convert a less toxic drug, 5-fluorocytosine (5-fc), to 5-fu inside the stem cells, and the chemotherapy can then seep out into the tumor, producing a lethal by-stander effect.

该基因可在干细胞中将毒性小的5 -氟胞嘧啶(5 - FC)转变为5 - FU，该化疗药物由干细胞进入肿瘤细胞，产生致死性的旁观者效应。

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