In one experiment 60% of mice missing something called the gamma interferon receptor on their cells got tumors after being exposed to a carcinogen, versus only 15% of normal mice.

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The researchers found that while two-thirds of infants with biliary atresia produced a cytokine called gamma-interferon, the protein was not found in any of the samples of infants with cholestasis.

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They found that the gene interacts with a key part of the immune system, a chemical called interferon gamma.

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