Yeast cells were grown in large numbers with this plasmid inside, they expressed the plasmid and so you made Hepatitis B surface antigen not in people but in cell culture where it was not normally formed.

体内携带这种质粒的酵母细胞大量增殖,它们表达质粒,因此,乙型肝炎表面抗原不是在人体内,而是在细胞培养环境下,以非正常方式形成的

耶鲁公开课 - 生物医学工程探索课程节选

The controversy arose in early 2012, when reports began to surface that newly formed tea-party and other conservative groups that had applied for tax-exempt status were receiving letters from the IRS asking for disclosure of their donors and other information that typically isn't requested of groups making such applications.

WSJ: IRS Apologizes for Scrutiny of Conservative Groups

The surface cooled, a crust formed, and oceans condensed upon it.

NEWYORKER: The Martian Chroniclers

Detailed studies of the surface indicate that these were formed by a lake caused by the flow of underground water that periodically made its way to the bottom of the crater.

FORBES: NASA Finds Remains Of Ancient Martian Lake