According to the“folding pathway theory”, the formation of intermediate is a key step in protein folding to reduce the searching scope for protein refolding.
“折叠途径”学说认为,在蛋白质折叠途径中必然有中间体的产生,这样才能减少蛋白质折叠所搜索的空间范围,解决“Levinthal佯谬”。
参考来源 - HAb18G/CD147胞外片段蛋白质折叠复性研究·2,447,543篇论文数据，部分数据来源于NoteExpress
A schematic flow chart of major oxidative folding and reductive unfolding pathway of AILP was proposed.
本文绘出了AILP的主要氧化折叠和还原解折叠途径草图。
The existing of intermediate in the process of protein unfolding is necessary for studying the kinetic folding and unfolding pathway of protein.
蛋白变性过程中间体的存在是蛋白变性及复性动力学研究中不可缺少的证据。
Most of the proteins examined so far proceed oxidative refolding via multiple pathways rather than a single and specific pathway. This is consistent with the folding energy landscape theory.
在已研究过的蛋白质中，大多数蛋白质都是沿着多途径而非单一、特定的途径进行氧化重折叠，这与折叠能量景观学说是一致的。
应用推荐