Objective to investigate the effect of flutamide on laryngeal carcinoma cell lines HEP-2 apoptosis.
目的观察氟硝丁酰胺对喉鳞癌细胞株hep 2的生长调控作用。
Furthermore, androgen up-regulation of intracellular ar protein was partially inhibited (50%) by nonsteroidal androgen antagonist, flutamide.
雄激素拮抗剂氟他胺也能够部分抑制(5 0 %)睾酮对细胞内AR蛋白水平的上调作用。
CONCLUSIONS Androgen can autoregulate the expression of androgen receptor in MCF-7 breast cancer cell line. Flutamide and hydroxyflutamide up regulate the expression of androgen receptor.
结论MCF-7乳腺癌细胞株中雄激素受体存在自动调节，氟他胺和羟基氟他胺上调雄激素受体的表达。
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