Fluticason propionate(1) in overall yield of 60.1% was synthesized from Flumethasone by oxidation, esterification, acylation, alcoholysis and fluoromethylation.
以双氟美松为原料，经氧化、 酯化、 酰化、 醇解和氟甲基化反应制得氟替卡松丙酸酯（1），总收率60。
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