Objective To investigate the relationship between hepatic fibrosis and hepatic stellate cell (HSC).
目的研究肝星状细胞(HSC)与肝纤维化和肝硬化的关系。
This paper briefly reviews the hepatic stellate cells (HSC) activation and proliferation-related signal transduction pathway and explores the role in the pathogenesis of liver fibrosis.
本综述以肝星状细胞激活与增殖相关信号转导通路为中心，探讨其在肝纤维化发病作用方面的作用机制。
Conclusion matrine can inhibit HSC proliferation and induce apoptosis of HSC, which might be one of the mechanisms of matrine to counteract liver fibrosis.
结论苦参碱可抑制HSC增殖、诱导HSC凋亡，可能是苦参碱抗肝纤维化的机制之一。
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