"This is the first year it's been prominent, extremely noticeable,' Fisher said.
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extremely noticeable
非常明显的
以上为机器翻译结果，长、整句建议使用 人工翻译 。
The skin is thin to the touch and extremely loose, this being more especially noticeable about the head and neck, where it hangs in deep folds.
皮肤的质地(触摸)薄，非常松弛，这一点在头部和颈部更加明显，在这些部位，皮肤松松地挂着，有很深的皱纹。
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It affects the sufferers ability to control their muscles and can vary from being barely noticeable to extremely severe.
BBC: Disabled person
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