Life lived from this perspective is characterized by a general condition of well-being and happiness punctuated by moments of extreme doubt, sorrow and pain.

从这样的角度活着，大体情况下是幸福快乐的，只是不时地会被某些极端的怀疑、悲伤和痛苦时刻所打扰。

youdao

If a person offend you, and you are in doubt as to whether it was intentional or not, do not resort to extreme measures; simply watch your chance and hit him with a brick. That will be sufficient.

如果有人得罪了你们，你们要犹豫一番，看看是存心的还是无意的，不要采取极端的做法；只要看好机会用砖块打他一下，那就足够了。

youdao

This shatters doubt, limiting beliefs and builds extreme confidence.

这会打破怀疑、局限性的信念以及建立极端自信。

youdao

There is not the slightest doubt, then, that extreme altitude tips the balance towards the home side.

BBC: Tim Vickery column

The irony is that Democrats have found, in Mr. Waxman, an even more extreme antibusiness tribune, who will no doubt use his new powers to go after any concern that turns a profit but refuses to pay his party the obeisance of campaign cash and regulatory submission.

WSJ: The Waxman Democrats

's latest supposedly authoritative report on extreme weather events, which is tinged with admissions of doubt and uncertainty?

WSJ: Stephens: The Great Global Warming Fizzle