In recent weeks, considerable effort has been dedicated to the advancement of my career. Long hours and tight deadlines have left me exhausted both physically and mentally.

近几个星期以来，为了升迁等事务，我付出相当多的精力，长时间的工作与迫在眉睫的工作日程让我心力交瘁和疲于奔命。

youdao

The long war of attrition exhausted the strength of both countries.

这场长期的消耗战耗尽了两国的力量。

《新英汉大辞典》

Since both of us were thoroughly exhausted, we decided to accommodate ourselves here overnight.

我们走累了，决定在这里过夜。

youdao

Our house is not kept near the way it used to be, we are both exhausted and their is little to no time to focus on the marriage because we are spread way too thin.

FORBES: Magazine Article

The weekend passed in a rainy, exhausted blur, as both Thomas and I had a sickness bug.

BBC: Marine wife on coping while husband's in Afghanistan

Sometimes both sides are exhausted, enabling skilful mediators to coax their leaders into negotiations.

ECONOMIST: Good news from Sudan and Senegal; disappointment in Uganda