The best animal model of exencephaly induced by RA was established with the maternal administration of 30mg/kg RA on E7.75 that results in 94.34%exencephaly rate on E10.5 and 76.92%on E16.5.2.
E7.75灌服30mg/kgRA可诱导94%(E10.5)/76.9%(E16.5)露脑畸形胚胎发生率,是本实验确定的最佳致畸动物模型。
参考来源 - Wnt信号通路与过量维甲酸致昆明小鼠神经管畸形的相关性研究·2,447,543篇论文数据，部分数据来源于NoteExpress
以上来源于: WordNet
There are 96 neural malformation with more common hydrocephalus anencephaly exencephaly.
其中中枢神经系统畸形96例，较常见的有脑积水。
Results There are 96 neural malformation with more common hydrocephalus anencephaly exencephaly and spina bifida in all malformations of 359 cases accounting for 26.7%.
结果共检出胎儿畸形359例，其中中枢神经系统畸形96例（26.7%），较常见的有脑积水、无脑畸形、露脑畸形及脊柱裂。
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