OBJECTIVE:To study the factor of influencing drug release from diclofenac sodium(DS)tablet coated with ethylcellulose aqueous dispersion.
目的:考察影响双氯芬酸钠乙基纤维素水性分散体包衣片体外释药的因素。
The amount of plasticizer, film thickness, curing temperature and curing time effect the release of the DS from the tablet coated with ethylcellulose aqueous dispersion.
结论 :乙基纤维素水性分散体可作为缓释衣膜材料。增塑剂用量、衣膜厚度、后处理温度、后处理时间等因素均影响药物的释放。
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