AIM: To establish a new simple and steady diabetic ulcer model for the clinical and basic study of diabetic skin ulcer.

目的：为适应糖尿病皮肤溃疡的临床和基础研究，建立一种简单而稳定的新型糖尿病皮肤溃疡模型。

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The basic theory of molecular docking design was first briefly described, and then the concept of the key residues in the protein receptor was introduced to establish a new flexible docking model.

首先阐述了分子对接设计的基本原理，然后在蛋白质受体中引入关键残基的概念，建立了一个新的柔性分子对接模型。

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In this paper we establish a network optimization model for this practical problem, and study its basic properties and algorithmic aspects.

论文建立此类问题的网络优化模型，并研究其基本性质及算法问题。

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