Their characteristic of complex cooperative growth has been a barrier for separating myxobacteria, inhibiting the selection of Sorangium cellulosum mutants during the genetic engineering of the epothilone biosynthetic gene cluster, for example.
粘细菌这种协同成长的特性严重限制了粘细菌的分离纯化工作,如纤维堆囊菌埃博霉素生物合成改造后期突变株的分离纯化。
参考来源 - 微包埋培养技术的建立及其在粘细菌分离纯化中的应用This study was not only useful for the structure design of epothilone, but also provided a novel insight into the deeper mechanism of drug resistance.
本试验的研究成果为进一步改造埃博霉素和更加深入的研究抗耐药机制提供了理论指导和铺垫。
参考来源 - 新型埃博霉素衍生物诱导乳腺癌细胞凋亡机制的研究·2,447,543篇论文数据，部分数据来源于NoteExpress
以上来源于: WordNet
This study was not only useful for the structure design of epothilone, but also provided a novel insight into the deeper mechanism of drug resistance.
本试验的研究成果为进一步改造埃博霉素和更加深入的研究抗耐药机制提供了理论指导和铺垫。
The invention also provides a fermentation method for producing the epothilone B by the fermentation culture of the sorangium cellulosum by using the sorangium cellulosum fermentation medium.
本发明还提供了使用本发明的纤维堆囊菌发酵培养基发酵培养纤维堆囊菌生产埃坡霉素B的发酵方法。
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