Chronic kidney disease is subject to the double impact of genetic and epigenetic modification.

慢性肾脏疾病受到遗传因素和表观遗传修饰的双重影响。

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DNA methylation is an important epigenetic modification which regulates a number of biological processes.

DNA甲基化作为一种重要的表观遗传修饰，调节着机体许多生物学过程。

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Objective: With the research of tumor developing mechanism, epigenetic modification has become a new view.

目的：随着对肿瘤发生机制研究的不断深入，表观遗传修饰成为新的研究热点。

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But, in this case, the epigenetic modification could be inherited from either the mother or the father.

ECONOMIST: Genes are not all there is to heredity

In mammals, this kind of epigenetic modification has been assumed to last only during the life span of a particular animal, because such changes are usually erased in the sperm and egg cells.

ECONOMIST: Genes are not all there is to heredity