The drugs work by preventing an enzyme called tyrosine kinase from launching a signaling cascade that fuels tumor cell growth.

这些药物的作用机制是阻断酪氨酸激酶启动信号级联反应，后者可以促进肿瘤细胞生长。

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More problematic is the multifunctional role of thrombin, the terminal enzyme in the coagulation cascade, which is also capable of stimulating an inflammatory response.

更多需要了解的问题是有关凝血酶多重功能的作用，凝血酶是血凝级联反应的终酶，同时也具有诱发炎症反应的作用。

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The first step in the RAS cascade is the secretion of the enzyme renin by renal juxtaglomerular cells in response to low blood pressure, sympathetic activation, hypovolemia, and low sodium flux.

肾素-血管紧张素系统作用机制的第一步是肾近球细胞受到低血压、交感神经兴奋、低血容量及低钠流量的刺激而分泌肾素。

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A reaction performed by one enzyme creates a product that stimulates another enzyme that creates a product, and stimulates another enzyme, and through this cascade of reactions you amplify and carry the signal forward.

一种酶催化生成的产物会活化另一种酶,而它催化的产物又能激活其他酶,催化反应生成另一种产物,通过这层层反应,信号被放大,并不断向前传递

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Cox-2 inhibitors, developed with much hype in the mid-1990s, block an enzyme called cyclooxygenase-2, in so doing shutting off a wide-reaching cascade of biochemical signals that take the form of fats called prostaglandins.

FORBES: Pharma Prophet