Objective To establish a method for determining the entrapment efficiency of podophyllotoxin in ethosomes.
目的建立鬼臼毒素醇质体包封率的测定方法。
参考来源 - 微柱离心BACKGROUND: Ethosome is a new liposome with high deformability, high entrapment efficiency and permeating completely through skin. It is especially suitable for the carrier of external administration and cutaneous penetration.
背景:醇质体是一种新型脂质体,具有高变形性、高包封率的优点,能完整地透过皮肤,尤其适合作为外用给药和透皮给药载体。
参考来源 - 苦参碱醇质体的制备及其体外透皮性能·2,447,543篇论文数据,部分数据来源于NoteExpress
RESULTS The entrapment efficiency with passive loading was only 13.3%; while up to 84.6% with active loading method.
结果被动载药法得到的包封率仅有13.3%,主动载药法的包封率最高可达84 . 6 %。
ResultsThe entrapment efficiency with passive loading method was low, while up to 84.38% with active loading method.
结果被动载药法制备脂质体包封率较低,主动载药制备脂质体包封率为84.38%。
Aim To prepare Clarithromycin floating beads and investigate its buoyancy, entrapment efficiency and drug release behavior in vitro.
目的制备克拉霉素胃漂浮小丸,考察其漂浮性,包封率和体外释药行为。
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