This phenomenon is mostly seen in imprinted genes and X-chromosome inactivation where DNA methylation of promoter regions leads to repression of gene expression.
这种现象主要在印迹基因和X染色体失活区域看到,这些区域中的启动子区的DNA甲基化导致了基因表达的抑制。
Objective To investigate the effect of dual-target antisense RNA of hepatitis B virus (HBV) targeted to X and P region on replication and expression of HBV gene in HBV transgenic mice.
目的探讨针对乙型肝炎病毒(HBV)x、p双靶区反义RNA对乙型肝炎病毒转基因小鼠HBV复制和表达的影响。
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