Because these genes are carried on the X-chromosome, they are subject to a process known as X-chromosome inactivation.

由于这些基因存在于X染色体上，它们发生了X染色体失活的处理。

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X inactivation starts at the X inactivation center (XIC) and spreads throughout the chromosome.

失活开始于XIC，然后传播到整条染色体。

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Objective To explore the relationship between X - linked spondyloepiphyseal dysplasia tarda (SEDL) gene escaping X chromosome inactivation( XCI) and SEDL phenotype.

目的探讨X-连锁迟发性脊椎骨骺发育不良（SEDL）基因逃避X染色体失活（XCI）及与临床表型的关系。

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