Researchers at the Wellcome Trust Sanger Institute have discovered several other genes which play a part, but have now discovered a gene, PBRM1, which is mutated in around a third of cases.

英国剑桥大学韦尔科姆基金会桑格学院研究所的研究者发现，另外也有一些基因起着作用，但是目前仅发现一种PBRM1基因在约三分之一的患者中会发生基因突变。

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Findings by the Wellcome Trust Sanger Institute in Cambridge and two other institutes in the U.S. and Canada revealed each one of us receives up to 60 mutations in our genome from our parents.

来自英国剑桥大学的桑格研究院，以及美国和加拿大的相关研究机构透露，与父母一辈相比，我们中的每一个人的基因中都携带有60多处的突变。

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The report also said that researchers at the Wellcome Trust Sanger Institute in Britain also found that 84 per cent of genes known to be connected to human disease have a zebrafish counterpart.

该报道还称，英国韦尔·科姆基金会桑格研究所的研究人员还发现，84%的已知同人类疾病相关的基因在斑马鱼基因中都可以找到对应物。

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Stratton of the Wellcome Trust Sanger Institute, both of whom recorded 13 Hot Papers in 2011.

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Wellcome Trust Sanger Institute director Prof Mike Stratton said the results were "remarkable" and would "stand as a foundation stone for human biology for many years".

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"It's a sobering finding, " said Andrew Futreal, a co-author of the study who until recently was director of cancer genetics and genomics at Wellcome Trust Sanger Institute in London.

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