The problem of talents is very important to a country 's prosperity and decline, or ups and downs.

人才问题是关系到一个国家的盛衰和兴亡的重大问题。

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The history and reality of enterprise' s ups and downs show that trained employees know how to take advantage of new technique as no trained employees were victim of it.

企业兴衰的历史和现实证明：受过培训的员工懂得如何利用新技术，而无知的员工则是新技术的牺牲品。

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The program sets forth steps for helping children learn to motivate themselves and cope with life's ups and downs.

WSJ: Tools for Building Self-Esteem in Kids

It's been one of the reasons coach Leslie Frazier and GM Rick Spielman have been so patient and supportive through Ponder's ups and downs.

NPR: Vikings Agree To Terms With WR Greg Jennings

And finally, here are some of 2012's ups and downs in pictures.

BBC: Your highlights of 2012 in drawings