Objective To analyze the role and location of ubiquitin-dependent proteolysis pathway (UPP) in PC12 cells transfected by plasmids with spinocerebellar ataxia type 3 (SCA3) gene.
目的分析泛素依赖的蛋白水解通路(UPP)在转染了脊髓小脑性共济失调3型(SCA3)基因的PC 12细胞中的定位及作用。
P42 is one subunit of 19s regulatory complex of 26s proteasome in ubiquitin-proteasome pathway, and it is also one subunit of modulator, which is 19s regulatory complex dependent.
p 42是泛素蛋白水解酶通路中26s蛋白水解酶复合体19s帽状调节复合物的一个亚基，也是组成19s调节复合物依赖的蛋白水解酶调节子的一个组成成分。
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