In this paper, tetramethylpyrazine hydrochloride (TMPH), which is used for angina pectoris clinically, was selected as a water-soluble model drug to prepare timed release pellets.
本文选择临床上用于治疗心绞痛的药物盐酸川芎嗪(TMPH)作为水溶性模型药制备定时释药微丸。
The timed release pellets consist of 5 laminar layers from the center to the outside :the core, the drug layer, the swelling agent layer , the block layer and the controlled layer .
该脉冲微丸由5层结构组成，从内而外分别是丸芯、药物层、溶胀层、阻滞层和水不溶性控释层。
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