They are talking about the greatest inventions that have made a big difference to our daily life.

他们正在谈论那些对日常生活有重大影响的最伟大的发明。

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Imagine if everyone thought that they could make a difference and everyone did just one little thing, changed one little habit, or made one different choice.

想象一下这样的场景吧：每一个人都认为他们与此有关并且每一个人都做了一件细微的事情、改变一个细微的习惯或者做出一个不同的选择。

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I have worked with teams where running regular heartbeat retrospectives made a big difference in the long term but because the changes were gradual and slow they don't make great headlines.

我曾工作过一些团队，他们长期进行正规的心跳回顾已经使其发生了很大的变化，但这种改变是逐步的而缓慢的，他们并没有制造头条新闻。

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These were then selected and implanted back into the mouse brain to see if they made a difference.

BBC: NEWS | Health | Mouse cloned to cure Parkinson's

Although television took off in the late 1940s, the 1960 Kennedy-Nixon debates were the first time they made a difference in a presidential race.

FORBES: Commentary

As a member of the Kiwanis Club of Garland, Texas, and an advisor to a K-Kids club, I wanted to find a service project that would not only be easy for the kids to participate in, but one that they could feel good about and know they had made a difference in the life of someone else.

WHITEHOUSE: One Shoe at a Time