I feel there is something lacking in my life.

我觉得我的生活中缺少点什么。

《牛津词典》

There is something about music that distinguishes it from all other art forms.

音乐中一些因素使之有别于其他艺术形式。

《柯林斯英汉双解大词典》

There is something special about this place.

这个地方有几分特别。

《牛津词典》

"There is something about that stretch that made me feel so much more vulnerable and susceptible and exposed to the natural conditions.

VOA: special.2011.03.23

There is something insidious and culturally malicious and powerful about the social conservatism of what is thought to be his voice.

人们认为弥尔顿宣扬的是社会保守主义,社会保守主义中有种隐藏的，文化上有害且强大的因素。

耶鲁公开课 - 弥尔顿课程节选

So you can ask if there is something else that is occupying their mind by using an "Is there" question.

所以你可以用“Is there”问句来问问他们是否有别的什么事让他们心神不宁。

Is there 课堂 - SpeakingMax英语口语达人

And I'm wondering if there is something, also, that comes out of indigenous New Zealand culture.

NPR: Fat Freddy's Drop Blends Reggae, Soul And DJ Culture

There is something calming about the sense of reality, whether of life or death.

NPR: Excerpt: 'Esther's Inheritance'

There is something to be said for companies that are in survival mode, however.

FORBES: Will Nook HD Succumb to Amazon's Supremacy?