Method: carvedilol solid dispersions were prepared by solvent-melting and coevaporation methods with PEG-6000 and PVP as carriers, the study on the dissolution was conducted in vitro.
方法:以聚乙烯吡咯烷酮(PVP)、聚乙二醇-6000(PEG-6000)为载体,溶剂法和溶剂熔融法制备固体分散体,并进行体外溶出度研究。
Fenofibrate solid dispersion tablets were prepared by solvent melting method using PEG4000 and sodium lauryl sulfate.
PEG4000十烷硫酸钠体,溶剂-熔融制备非诺贝特固体散体,再适辅混合压片制非诺贝特固体散片。
METHODS Preparing the solid dispersion by melting method at different drug-to-PEG ratios with different PEG moleculars and studying the preparation with dissolution rate in vitro and DSC method.
方法以不同分子量不同比例的聚乙二醇为载体,以熔融法制备固体分散体,并进行体外溶出度研究和DSC扫描。
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