Several factors, such as defects in chromosome segregation and DNA damage response, failure of cell cycle checkpoint, telomere dysfunction, may cause chromosomal instability.

多种细胞机制功能障碍将导致染色体不稳定性，包括染色体分离、DNA损伤反应、细胞周期检查点、端粒功能等。

youdao

The prison administration gave Dellelo five years in the Departmental Disciplinary Unit of the Walpole prison, its hundred-and-twenty-four-cell super-maximum segregation unit.

NEWYORKER: Hellhole