Problems existed in simulation scale-up, engineering design, equipment manufacture and materials properties are main causes for the slow technical progress of the ammonia industry in China.

模拟放大、工程设计、设备制造和材料性能的问题，是我国合成氨工业技术进步缓慢的主要原因。

youdao

Manufacturing, process or "scale-up" engineering has primary responsibility for designing quality into the manufacturing processes.

制造，工艺或量产工程部门负有制造流程设计质量的基本责任。

youdao

It sounds great but I question the usual scale-up and engineering required to inaugurate a huge infrastructure based on biogas.

FORBES: U.K. Joins Europe On Biogas 'Waste Into Energy' Strategy